Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KRAS | P01116 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29122348 | 1.00 | TEAD1 (0.37) | TEAD1TEAD4TEAD2PTGDR2CNR1 | |
| SCHEMBL29121565 | 0.85 | BTK (0.45) | CNR1EGFRBTKFPR2KRAS | |
| SCHEMBL29121569 | 0.85 | BTK (0.45) | CNR1EGFRBTKFPR2KRAS | |
| SCHEMBL30676570 | 0.85 | BTK (0.45) | CNR1EGFRBTKFPR2KRAS | |
| SCHEMBL30676388 | 0.85 | BTK (0.45) | CNR1EGFRBTKFPR2KRAS | |
| SCHEMBL29121705 | 0.85 | BTK (0.45) | CNR1EGFRBTKFPR2KRAS | |
| SCHEMBL29122382 | 0.82 | TEAD1 (0.40) | TEAD1TEAD4TEAD2PTGDR2CNR1 | |
| SCHEMBL29122614 | 0.80 | POLB (0.35) | CNR1BTKFPR2L3MBTL3L3MBTL1 | |
| SCHEMBL29121918 | 0.80 | TEAD1 (0.38) | TEAD1TEAD4TEAD2CNR1KDM5A | |
| SCHEMBL29121743 | 0.80 | TEAD1 (0.38) | TEAD1TEAD4TEAD2KDM5APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |