Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.37 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 3/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29121571 | 1.00 | L3MBTL1 (0.40) | L3MBTL1TSHRHTTMAPK8SRC | |
| SCHEMBL29122594 | 1.00 | L3MBTL1 (0.40) | L3MBTL1TSHRHTTMAPK8SRC | |
| SCHEMBL29122002 | 0.94 | MAPK8 (0.39) | L3MBTL1TSHRHTTMAPK8SLC2A1 | |
| SCHEMBL29122339 | 0.93 | L3MBTL1 (0.41) | L3MBTL1TSHRHTTMAPK8SLC2A1 | |
| SCHEMBL29121823 | 0.85 | MAPK8 (0.45) | L3MBTL1TSHRHTTMAPK8ELANE | |
| SCHEMBL29122733 | 0.85 | L3MBTL1 (0.43) | L3MBTL1TSHRHTTMAPK8ELANE | |
| SCHEMBL28387098 | 0.84 | MAPK8 (0.47) | L3MBTL1TSHRHTTMAPK8ELANE | |
| SCHEMBL29121796 | 0.82 | SLC2A1 (0.44) | L3MBTL1TSHRHTTMAPK8SLC2A1 | |
| SCHEMBL29121562 | 0.80 | ELANE (0.51) | TSHRELANEPDE1APDE1BPDE1C | |
| SCHEMBL29121920 | 0.80 | ELANE (0.51) | TSHRELANEPDE1APDE1BPDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120419-A | KLK5 bicyclic heteroaromatic inhibitors | 拜奥克里斯特制药公司 | 2023-11-24 | — | — | CN | disclosed |