Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30101747 | 1.00 | PCSK9 (0.66) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL29123519 | 0.88 | PCSK9 (0.70) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL30101699 | 0.88 | PCSK9 (0.70) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL30101633 | 0.87 | PCSK9 (0.75) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL29123611 | 0.87 | PCSK9 (0.75) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL29123598 | 0.87 | PCSK9 (0.73) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL30101767 | 0.87 | PCSK9 (0.73) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 | |
| SCHEMBL29123656 | 0.84 | PCSK9 (0.62) | PCSK9ALDH1A1KDM4ECYP2D6CYP2C9 | |
| SCHEMBL30101616 | 0.84 | PCSK9 (0.62) | PCSK9ALDH1A1KDM4ECYP2D6CYP2C9 | |
| SCHEMBL30101685 | 0.82 | PCSK9 (0.75) | PCSK9SMN1; SMN2ALDH1A1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109011-B | Benzothiazole compound, preparation method and application | 河北师范大学 | 2023-12-15 | — | — | CN | disclosed |