Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9286585 | 0.84 | NOTUM (0.40) | NOTUMKDM4EHCRTR1HCRTR2 | |
| SCHEMBL29124819 | 0.78 | EGLN2 (0.38) | NOTUMKDM4EALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL7468796 | 0.72 | MYC (0.53) | KDM4EALDH1A1GAAHCRTR1HCRTR2 | |
| SCHEMBL18367779 | 0.72 | ALDH1A1 (0.47) | NOTUMKDM4EALDH1A1GAAHCRTR1 | |
| SCHEMBL13041779 | 0.72 | KDM4E (0.47) | ATRPSMD14KDM4EGLAALDH1A1 | |
| SCHEMBL19481013 | 0.71 | HCRTR1 (0.41) | NOTUMHCRTR1HCRTR2 | |
| SCHEMBL17948707 | 0.71 | KDM4E (0.46) | ATRPSMD14KDM4EGLAALDH1A1 | |
| SCHEMBL31720064 | 0.71 | KDM4E (0.46) | ATRPSMD14KDM4EGLAALDH1A1 | |
| SCHEMBL23500690 | 0.69 | ATR (0.48) | ATRPSMD14KDM4EGLAALDH1A1 | |
| SCHEMBL17545204 | 0.69 | KDM4E (0.53) | ATRPSMD14KDM4EGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |