Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 5/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29418409 | 0.90 | BTK (0.40) | BTKKLKB1ROCK2DGAT2ROCK1 | |
| Hydrochloric Acid SCHEMBL25258861 | 0.90 | BTK (0.40) | BTKKLKB1ROCK2DGAT2ROCK1 | |
| SCHEMBL29124664 | 0.89 | BTK (0.45) | BTKKLKB1DGAT2 | |
| SCHEMBL29124627 | 0.89 | BTK (0.45) | BTKKLKB1DGAT2 | |
| SCHEMBL29124666 | 0.89 | BTK (0.45) | BTKKLKB1DGAT2 | |
| SCHEMBL29124700 | 0.89 | DGAT2 (0.35) | BTKROCK2DGAT2ROCK1CDC42BPB | |
| SCHEMBL29124675 | 0.87 | BTK (0.45) | BTKKLKB1DGAT2 | |
| SCHEMBL29124808 | 0.87 | BTK (0.36) | BTKKLKB1DGAT2ROCK1CDC42BPB | |
| SCHEMBL29124753 | 0.85 | BTK (0.46) | BTKKLKB1DGAT2 | |
| SCHEMBL29124729 | 0.85 | BTK (0.43) | BTKROCK2DGAT2ROCK1CDC42BPB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |