Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124649 | 0.84 | BTK (0.53) | BTKKLKB1CRBNMIF | |
| SCHEMBL29418492 | 0.77 | BTK (0.54) | BTKKLKB1MIF | |
| SCHEMBL23605779 | 0.77 | BTK (0.54) | BTKKLKB1MIF | |
| SCHEMBL25173782 | 0.76 | BTK (0.56) | BTKKLKB1 | |
| SCHEMBL30913578 | 0.76 | BTK (0.56) | BTKKLKB1 | |
| SCHEMBL29418287 | 0.76 | BTK (0.54) | BTKKLKB1CRBN | |
| SCHEMBL25224811 | 0.76 | BTK (0.54) | BTKKLKB1CRBN | |
| SCHEMBL23304290 | 0.76 | BTK (0.55) | BTKKLKB1CRBN | |
| SCHEMBL25214690 | 0.75 | BTK (0.51) | BTKKLKB1CRBN | |
| SCHEMBL29418616 | 0.75 | BTK (0.51) | BTKKLKB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917279-A | BTK inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-10-20 | — | — | CN | disclosed |