Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 7/20 | 0.51 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25214690 | 1.00 | BTK (0.51) | BTKCYP46A1GPR119CRBNKLKB1 | |
| SCHEMBL25244549 | 0.90 | BTK (0.51) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL29418443 | 0.90 | BTK (0.51) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL29418287 | 0.88 | BTK (0.54) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL25224811 | 0.88 | BTK (0.54) | BTKCYP46A1CRBNKLKB1 | |
| SCHEMBL25270244 | 0.87 | BTK (0.50) | BTKGPR119CRBNKLKB1MEN1 | |
| SCHEMBL29418498 | 0.87 | BTK (0.50) | BTKGPR119CRBNKLKB1MEN1 | |
| SCHEMBL25216839 | 0.85 | CYP46A1 (0.40) | BTKCYP46A1GPR119MEN1KMT2A | |
| SCHEMBL29418478 | 0.85 | CYP46A1 (0.40) | BTKCYP46A1GPR119MEN1KMT2A | |
| SCHEMBL29418334 | 0.83 | BTK (0.46) | BTKCYP46A1GPR119CRBNKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192587-A1 | BTK INHIBITORS | Biogen MA Inc. (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022032019-A1 | BTK INHIBITORS | BIOGEN MA INC. (US) | 2022-02-10 | — | — | WO | disclosed |