Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.37 |
| ▸ | CCR7 | P32248 | 1/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29124870 | 0.83 | SYK (0.37) | SYKAURKAAURKBL3MBTL1 | |
| SCHEMBL29124862 | 0.80 | SYK (0.36) | SYKGAAAURKAAURKBL3MBTL1 | |
| SCHEMBL30046588 | 0.80 | CCR7 (0.31) | CCR7 | |
| SCHEMBL27157693 | 0.78 | CCR7 (0.30) | CCR7 | |
| SCHEMBL22939319 | 0.77 | SYK (0.39) | SYKL3MBTL1 | |
| SCHEMBL29593210 | 0.77 | SYK (0.39) | SYKL3MBTL1 | |
| SCHEMBL19738205 | 0.77 | SYK (0.39) | SYKAURKAL3MBTL1 | |
| SCHEMBL19738337 | 0.77 | SYK (0.39) | SYKL3MBTL1 | |
| SCHEMBL19738339 | 0.76 | SYK (0.39) | SYKL3MBTL1 | |
| SCHEMBL29124861 | 0.75 | IDO1 (0.42) | AURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117241803-A | Purine nucleosides, intermediates and methods of making the same | 阿斯特罗赛特制药公司 | 2023-12-15 | — | — | CN | disclosed |