Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125767 | 0.84 | ALDH1A1 (0.62) | NISCHRXRARXRBRXRGALOX15 | |
| SCHEMBL29125726 | 0.82 | ALDH1A1 (0.56) | NISCHALDH1A1MAPTSYKKDM4E | |
| SCHEMBL29125684 | 0.75 | ALDH1A1 (0.48) | ALOX15ALDH1A1TP53KDM4EGAA | |
| SCHEMBL29125867 | 0.75 | ALDH1A1 (0.45) | ALOX15ALDH1A1TP53MAPTSYK | |
| SCHEMBL29125866 | 0.75 | NOTUM (0.52) | RXRARXRBALDH1A1TP53MAPT | |
| SCHEMBL9731628 | 0.75 | PTGS1 (0.56) | ALOX15ALDH1A1HSD17B10PTGS1 | |
| SCHEMBL29125729 | 0.74 | ALDH1A1 (0.44) | ALOX15ALDH1A1SYKGAANOTUM | |
| SCHEMBL29125794 | 0.71 | MAPT (0.47) | ALOX15ALDH1A1MAPTSYKGAA | |
| SCHEMBL29125970 | 0.70 | ALDH1A1 (0.47) | ALOX15ALDH1A1TP53GAANOTUM | |
| SCHEMBL20187655 | 0.70 | NOTUM (0.39) | SYKNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |