Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125733 | 0.87 | ALDH1A1 (0.39) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL29125929 | 0.84 | TSHR (0.48) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL29125771 | 0.80 | KMT2A (0.54) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL29128476 | 0.77 | DPYD (0.33) | ALDH1A1HTTMAPTKDM4E | |
| SCHEMBL29126003 | 0.77 | TSHR (0.49) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL29125948 | 0.73 | KMT2A (0.53) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL29125763 | 0.73 | TSHR (0.39) | TSHRKMT2AMMP13ALDH1A1LMNA | |
| SCHEMBL29125687 | 0.73 | TSHR (0.44) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL30788511 | 0.72 | TSHR (0.49) | TSHRKMT2AMMP13ALDH1A1CYP1A2 | |
| SCHEMBL29125759 | 0.71 | ALDH1A1 (0.39) | TSHRKMT2AMMP13ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |