Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125851 | 0.87 | ALDH1A1 (0.47) | MTNR1BALDH1A1LMNAKDM4ETP53 | |
| SCHEMBL29125977 | 0.84 | MAPT (0.38) | NOTUMMTNR1BALDH1A1MTNR1ASORT1 | |
| SCHEMBL29125926 | 0.84 | NOTUM (0.38) | NOTUMMTNR1BALDH1A1MTNR1AKDM4E | |
| SCHEMBL29128276 | 0.80 | DAO (0.34) | ALDH1A1KDM4EMAPTHPGDELANE | |
| SCHEMBL29128551 | 0.75 | DAO (0.32) | — | |
| SCHEMBL29125689 | 0.75 | NOTUM (0.40) | NOTUMMTNR1BALDH1A1LMNAMTNR1A | |
| SCHEMBL29125724 | 0.74 | ALDH1A1 (0.38) | NOTUMALDH1A1LMNAKDM4ESYK | |
| SCHEMBL29125884 | 0.74 | ALDH1A1 (0.53) | NOTUMALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL29125949 | 0.74 | ALDH1A1 (0.33) | MTNR1BALDH1A1LMNAMTNR1AKDM4E | |
| SCHEMBL29125739 | 0.73 | NOTUM (0.43) | NOTUMALDH1A1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |