Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 7/20 | 0.38 |
| ▸ | THRA | P10827 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.38 |
| ▸ | PCNA | P12004 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8107388 | 1.00 | ESR1 (0.40) | ESR1KMT2ABLMALOX15PMP22 | |
| SCHEMBL7094989 | 0.86 | KDM4E (0.50) | KMT2ABLMALOX15PMP22USP2 | |
| SCHEMBL7094986 | 0.86 | KDM4E (0.50) | KMT2ABLMALOX15PMP22USP2 | |
| SCHEMBL2912668 | 0.79 | ESR1 (0.40) | ESR1KMT2ABLMALOX15THRB | |
| SCHEMBL4658680 | 0.78 | BLM (0.47) | ESR1KMT2ABLMALOX15PMP22 | |
| SCHEMBL4658683 | 0.78 | BLM (0.47) | ESR1KMT2ABLMALOX15PMP22 | |
| SCHEMBL7523284 | 0.74 | KDM4E (0.50) | ESR1BLMALOX15PMP22LMNA | |
| SCHEMBL6286721 | 0.73 | KMT2A (0.43) | KMT2ABLMALOX15PMP22MEN1 | |
| SCHEMBL29634956 | 0.73 | BLM (0.53) | KMT2ABLMALOX15PMP22LMNA | |
| SCHEMBL10962857 | 0.71 | LCK (0.53) | ESR1KMT2ATSHRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042286-B1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | CRAGMONT PHARMACEUTICALS LLC (US) | 2010-08-25 | — | — | EP | disclosed |
| EP-1042286-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | Wei, Edward T. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033799-A1 | GAMMA-GLUTAMYL AND BETA-ASPARTYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | WEI EDWARD T (US) | 1999-07-08 | — | — | WO | disclosed |
| US-5916878-A | DIPEPTIDE OF EITHER GAMMA-GLUTAMYL-L-TRYPTOPHAN OR BETA-ASPARTYL-L-TRYPTOPHAN; ADMINISTERING TO THE PATIENTS TO REDUCE THE RISKS INFECTIONS FROM MICROORGANISM | Wei, Edward T. (US) | 1999-06-29 | — | — | US | disclosed |
| US-5744452-A | IMMUNE SYSTEM DISORDERS, AIDS | Wei, Edward T. (US) | 1998-04-28 | — | — | US | disclosed |
| WO-1997019691-A1 | GAMMA-L-GLUTAMYL CONTAINING IMMUNOMODULATOR COMPOUNDS AND METHODS THEREWITH | WEI, EDWARD, T. (US) | 1997-06-05 | — | — | WO | disclosed |