Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | DBH | P09172 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7094989 | 1.00 | KDM4E (0.50) | KDM4EGAARECQLDBHCA2 | |
| SCHEMBL7523284 | 0.87 | KDM4E (0.50) | KDM4EGAARECQLDBHCA2 | |
| SCHEMBL8107388 | 0.86 | ESR1 (0.40) | KDM4EGAARECQLDBHCA2 | |
| SCHEMBL2912663 | 0.86 | ESR1 (0.40) | KDM4EGAARECQLDBHCA2 | |
| SCHEMBL4658683 | 0.81 | BLM (0.47) | KDM4EGAARECQLCA2CA1 | |
| SCHEMBL4658680 | 0.81 | BLM (0.47) | KDM4EGAARECQLCA2CA1 | |
| SCHEMBL8935094 | 0.77 | CA12 (0.43) | KDM4EGAARECQLDBHCA2 | |
| SCHEMBL6286721 | 0.77 | KMT2A (0.43) | GAACA2CA1ALOX15BLM | |
| SCHEMBL29634956 | 0.76 | BLM (0.53) | GAARECQLALOX15BLMPMP22 | |
| SCHEMBL1970885 | 0.74 | BLM (0.47) | KDM4EGAARECQLCA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0635577-B1 | Screen for inhibitors of melanin biosynthesis | BASF AG (DE) | 2003-08-27 | — | — | EP | disclosed |
| US-5538752-A | APPLYING PRESERVATIVES TO PLANTS TO INHIBIT DECAY | REGENTS OF THE UNIV. OF MINNESOTA (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0635577-A2 | Screen for inhibitors of melanin biosynthesis | AMERICAN CYANAMID COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0363792-B1 | Melanin production | BIOSOURCE GENETICS CORP (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1990004029-A1 | MELANIN PRODUCTION | BIOSOURCE GENETICS CORPORATION (US) | 1990-04-19 | — | — | WO | disclosed |
| EP-0363792-A1 | Melanin production | BIOSOURCE GENETICS CORPORATION (US) | 1990-04-18 | — | — | EP | disclosed |