SCHEMBL29127601

SCHEMBL29127601

O=P(O)(O)OC(Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.47
PGK1 P00558 3/20 0.44
PGK2 P07205 3/20 0.44
SRC P12931 2/20 0.43
CYP1A2 P05177 1/20 0.43
TSHR P16473 2/20 0.41
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
PTPN5 P54829 2/20 0.38
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
HPGD P15428 1/20 0.36
PDE3A Q14432 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KCNN4 O15554 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CFTR P13569 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29049152 0.83 PTPN1 (0.47) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL1070250 0.78 PTPN1 (0.50) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL5514428 0.77 PTPN1 (0.48) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL28219024 0.77 PTPN1 (0.48) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL11032371 0.76 PTPN1 (0.44) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL1955319 0.75 PTPN1 (0.47) PTPN1PGK1PGK2SRCTSHR
SCHEMBL1014613 0.75 ALDH1A1 (0.54) PTPN1PGK1PGK2SRCTSHR
SCHEMBL3865494 0.75 PTPN1 (0.47) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL18419392 0.73 PTPN1 (0.45) PTPN1PGK1PGK2SRCCYP1A2
SCHEMBL31692097 0.72 PTPN1 (0.53) PTPN1PGK1PGK2SRCTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117157279-A Preparation method of bicyclo compound and application of bicyclo compound as antibacterial agent 上海济煜医药科技有限公司 2023-12-01 CN disclosed