Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909662 | 0.86 | GSK3A (0.44) | GSK3AGSK3BCDK1 | |
| SCHEMBL2909976 | 0.85 | GSK3A (0.39) | GSK3AGSK3BCDK1 | |
| SCHEMBL2913331 | 0.84 | CDK1 (0.41) | GSK3AGSK3BCDK1 | |
| SCHEMBL2906860 | 0.83 | GSK3A (0.39) | GSK3AGSK3BCDK1 | |
| SCHEMBL2911937 | 0.82 | CDK1 (0.42) | GSK3AGSK3BCDK1 | |
| SCHEMBL2910066 | 0.82 | GSK3A (0.38) | GSK3AGSK3BCDK1 | |
| SCHEMBL2912012 | 0.81 | GSK3A (0.41) | GSK3AGSK3BCDK1 | |
| SCHEMBL2911578 | 0.81 | GSK3A (0.38) | GSK3AGSK3BCDK1 | |
| SCHEMBL2904171 | 0.81 | GSK3A (0.38) | GSK3AGSK3BCDK1 | |
| SCHEMBL2903761 | 0.81 | CDK1 (0.38) | GSK3AGSK3BCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537099-B1 | PYRROLE BASED INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2010-08-11 | — | — | EP | disclosed |