Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128486 | 0.81 | HTR1A (0.42) | HTR1AADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL29128459 | 0.81 | NPC1 (0.44) | ALDH1A1RAB9ALMNANPC1HPGD | |
| SCHEMBL29128393 | 0.77 | DAO (0.50) | ALDH1A1RAB9AUSP2PABPC1TDP1 | |
| SCHEMBL29128346 | 0.76 | DAO (0.43) | HTR1AALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL29128407 | 0.76 | MEN1 (0.49) | ALDH1A1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL30800030 | 0.75 | RXRB (0.37) | ALDH1A1MAPTHTTUSP2PABPC1 | |
| SCHEMBL29128292 | 0.74 | APP (0.41) | ALDH1A1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL29128299 | 0.70 | DPYD (0.36) | — | |
| SCHEMBL1081189 | 0.66 | MAPT (0.59) | HTR1AADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL29414783 | 0.66 | MAPT (0.59) | HTR1AADRA2AADRA2BADRA2CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |