Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ICMT | O60725 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29071735 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL29277397 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL29277420 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL9317815 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL8702147 | 1.00 | ALDH1A1 (0.63) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL11903655 | 0.98 | ALDH1A1 (0.64) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL16116060 | 0.94 | ALDH1A1 (0.66) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL14519061 | 0.92 | ALDH1A1 (0.71) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL31516344 | 0.88 | POLB (0.62) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL14448832 | 0.88 | POLB (0.62) | ALDH1A1NPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263933-A | Alpha-carboline derivative and synthesis method thereof | 湘潭大学 | 2023-12-22 | — | — | CN | claimed |
| CN-117263933-A | Alpha-carboline derivative and synthesis method thereof | 湘潭大学 | 2023-12-22 | — | — | CN | disclosed |