Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.33 |
| ▸ | CHUK | O15111 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | MELK | Q14680 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | AXL | P30530 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29987117 | 1.00 | IKBKB (0.33) | IKBKBCHUKPDE4AMELKLCK | |
| SCHEMBL31710599 | 0.81 | LPL (0.31) | — | |
| SCHEMBL3140900 | 0.80 | CA12 (0.36) | CHUKUCHL1 | |
| SCHEMBL30623051 | 0.80 | CA12 (0.36) | CHUKUCHL1 | |
| SCHEMBL15717180 | 0.80 | CHRNB4 (0.41) | IKBKBCHUKMELK | |
| SCHEMBL20295324 | 0.79 | CA12 (0.40) | UCHL1 | |
| SCHEMBL2404799 | 0.79 | LPL (0.38) | — | |
| SCHEMBL26985491 | 0.76 | MCHR1 (0.32) | — | |
| SCHEMBL16052531 | 0.75 | CHRNB4 (0.35) | MELK | |
| SCHEMBL30623027 | 0.75 | OPRL1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279896-A | Amino substituted pyrido ring compounds, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-12-22 | — | — | CN | disclosed |