Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28168624 | 0.96 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL26644608 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL28381950 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL29098766 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL29204851 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL28228941 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL28176306 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL29116846 | 0.93 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL28240025 | 0.93 | TSHR (0.53) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL25399402 | 0.89 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114686221-B | Semiconductor nanomaterial for up-conversion luminescence through surface plasmon resonance regulation and preparation method and application thereof | 暨南大学 | 2023-11-17 | — | — | CN | claimed |
| CN-114686221-A | Semiconductor nano material for regulating up-conversion luminescence by surface plasma resonance and preparation method and application thereof | 暨南大学 | 2022-07-01 | — | — | CN | claimed |
| CN-114686221-B | Semiconductor nanomaterial for up-conversion luminescence through surface plasmon resonance regulation and preparation method and application thereof | 暨南大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-114686221-A | Semiconductor nano material for regulating up-conversion luminescence by surface plasma resonance and preparation method and application thereof | 暨南大学 | 2022-07-01 | — | — | CN | disclosed |