Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28240025 | 0.96 | TSHR (0.53) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL4303342 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL2039900 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL9561381 | 0.92 | — | — | |
| Alcohol SCHEMBL25333131 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21409712 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21808784 | 0.92 | — | — | |
| Alcohol SCHEMBL21599246 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21801676 | 0.92 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ATDP1 | |
| Alcohol SCHEMBL21297005 | 0.92 | TSHR (0.60) | TSHRALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108300460-B | Nano sulfide near-infrared long-afterglow material and preparation and application thereof | 华南理工大学 | 2020-08-18 | — | — | CN | claimed |
| CN-108300460-A | A kind of nanometer sulfide near-infrared long-afterglow material and its preparation and application | 华南理工大学 | 2018-07-20 | — | — | CN | claimed |
| CN-116178051-B | Preparation method of rare earth oxide modified C/(C-) SiC-ZrC composite material | 中国科学院金属研究所 | 2024-06-04 | — | — | CN | disclosed |
| WO-2023176837-A1 | CERAMIC CONTINUOUS FIBER AND METHOD FOR PRODUCING SAME, AND CERAMIC MATRIX COMPOSITE MATERIAL INCLUDING SAME | 東ソー株式会社 | 2023-09-21 | — | — | WO | disclosed |
| CN-116178051-A | Preparation method of rare earth oxide modified C/(C-) SiC-ZrC composite material | 中国科学院金属研究所 | 2023-05-30 | — | — | CN | disclosed |
| CN-110407597-B | Rare earth oxide modified silicon carbide ceramic matrix composite material and preparation method thereof | 中国科学院上海硅酸盐研究所 | 2021-05-25 | — | — | CN | disclosed |
| CN-108300460-B | Nano sulfide near-infrared long-afterglow material and preparation and application thereof | 华南理工大学 | 2020-08-18 | — | — | CN | disclosed |
| CN-108300460-B | Nano sulfide near-infrared long-afterglow material and preparation and application thereof | 华南理工大学 | 2020-08-18 | — | — | CN | disclosed |
| CN-110407597-A | A kind of rare-earth oxide modified carbon/silicon carbide ceramic matrix composite and preparation method thereof | SHANGHAI INST CERAMICS CAS | 2019-11-05 | — | — | CN | disclosed |
| CN-108300460-A | A kind of nanometer sulfide near-infrared long-afterglow material and its preparation and application | 华南理工大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-108300460-A | A kind of nanometer sulfide near-infrared long-afterglow material and its preparation and application | 华南理工大学 | 2018-07-20 | — | — | CN | disclosed |
| CN-105295912-B | A kind of efficient green up-conversion luminescence laminated film and preparation method thereof | 大连民族大学 | 2017-07-11 | — | — | CN | disclosed |