Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RET | P07949 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129514 | 0.84 | TP53 (0.68) | TP53LMNARETALOX12HTT | |
| SCHEMBL29129596 | 0.83 | MAPT (0.48) | TP53LMNAHTTTSHRABCG2 | |
| SCHEMBL29129508 | 0.83 | KMT2A (0.61) | TP53LMNARETALOX12HTT | |
| SCHEMBL29129547 | 0.83 | KMT2A (0.65) | TP53LMNARETALOX12HTT | |
| SCHEMBL31566133 | 0.83 | TP53 (0.72) | TP53LMNARETALOX12HTT | |
| SCHEMBL29129513 | 0.81 | RET (0.68) | TP53LMNARETALOX12HTT | |
| SCHEMBL29129565 | 0.81 | MAPK14 (0.62) | TP53LMNARETALOX12HTT | |
| SCHEMBL29129511 | 0.80 | ABCG2 (0.74) | TP53LMNATSHRABCG2ALDH1A1 | |
| SCHEMBL29129570 | 0.77 | KDM4E (0.50) | TP53LMNARETALOX12HTT | |
| SCHEMBL29129555 | 0.77 | ABCG2 (0.51) | TP53LMNARETALOX12HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247370-A | Method for synthesizing thioflavonoids based on alkyne thiocarboxyl | 四川大学 | 2023-12-19 | — | — | CN | disclosed |