Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | PON1 | P27169 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129505 | 0.86 | ADORA3 (0.47) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL29129592 | 0.83 | TP53 (0.49) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL29129503 | 0.82 | MAPT (0.70) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL29129599 | 0.79 | ADORA3 (0.74) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL29129516 | 0.79 | TNKS (0.55) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL29839881 | 0.79 | ALDH1A1 (0.46) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL29129547 | 0.78 | KMT2A (0.65) | MAPTKDM4EADORA3ALDH1A1CYP3A4 | |
| SCHEMBL12181810 | 0.76 | PON1 (0.57) | MAPTKDM4EALDH1A1CYP3A4MEN1 | |
| SCHEMBL8642698 | 0.75 | MAOA (0.60) | MAPTKDM4EALDH1A1CYP3A4MEN1 | |
| SCHEMBL29129508 | 0.75 | KMT2A (0.61) | MAPTKDM4EADORA3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247370-A | Method for synthesizing thioflavonoids based on alkyne thiocarboxyl | 四川大学 | 2023-12-19 | — | — | CN | disclosed |