Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 6/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489084 | 0.82 | MIF (0.71) | MIFIDO1DAOGRIN2B | |
| SCHEMBL29069340 | 0.80 | MIF (0.69) | MIFIDO1DAOCES2TACR1 | |
| SCHEMBL8816811 | 0.80 | GABRA1 (0.37) | MIFRXRARXRBRXRG | |
| SCHEMBL1648872 | 0.80 | MIF (0.49) | MIFIDO1DAOCES2GRIN2B | |
| SCHEMBL199862 | 0.78 | CYP3A4 (0.32) | MIF | |
| SCHEMBL460071 | 0.76 | POLB (0.34) | MIFRXRARXRBRXRG | |
| SCHEMBL7873861 | 0.72 | IDO1 (0.47) | MIFIDO1DAOCES2TACR1 | |
| SCHEMBL5540436 | 0.72 | IDO1 (0.47) | IDO1DAOCES2TACR1RXRA | |
| SCHEMBL16798241 | 0.72 | MIF (0.41) | MIFIDO1DAOCES2 | |
| SCHEMBL15435871 | 0.72 | MIF (0.41) | MIFIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759564-B | Diaryl urea compound and its prepn and medicinal use | 中国医学科学院药物研究所 | 2023-09-26 | — | — | CN | disclosed |