Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672158 | 0.88 | NOTUM (0.54) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL20944192 | 0.88 | NOTUM (0.54) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL1869827 | 0.83 | NOTUM (0.51) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL28987542 | 0.82 | NOTUM (0.56) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL1188442 | 0.79 | NOTUM (0.57) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL29130080 | 0.78 | CA1 (0.37) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL24017285 | 0.78 | NOTUM (0.57) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL21609833 | 0.78 | NOTUM (0.50) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL31401414 | 0.76 | NOTUM (0.64) | NOTUMCA1CA2CA12CA7 | |
| SCHEMBL1868624 | 0.76 | NOTUM (0.64) | NOTUMCA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295736-A | Benzo [ C ] [2,6] naphthyridine derivatives, compositions thereof and therapeutic uses thereof | 剑桥实业有限公司 | 2023-12-26 | — | — | CN | disclosed |