Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butyramide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyramide SCHEMBL29130696 | 1.00 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyramide SCHEMBL17685288 | 0.94 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyramide SCHEMBL8555402 | 0.94 | — | — | |
| Butyramide SCHEMBL5681 | 0.94 | — | — | |
| Butyramide SCHEMBL29664015 | 0.94 | — | — | |
| Butyramide SCHEMBL27345575 | 0.94 | CES2 (0.53) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyramide SCHEMBL5983625 | 0.91 | FFAR3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyramide SCHEMBL28028738 | 0.91 | FFAR3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyramide SCHEMBL6760888 | 0.91 | FFAR3 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 | |
| Butyramide SCHEMBL16211050 | 0.90 | CES2 (0.50) | HDAC3HDAC1HDAC2HDAC8FFAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113797212-B | Synthesis method and activity research of antibacterial drugs containing mannose structure | 兰州大学 | 2023-12-22 | — | — | CN | claimed |
| CN-113797212-B | Synthesis method and activity research of antibacterial drugs containing mannose structure | 兰州大学 | 2023-12-22 | — | — | CN | disclosed |