Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212728 | 0.90 | POLB (0.48) | POLBEPHX2GAALMNAL3MBTL1 | |
| SCHEMBL12820384 | 0.89 | POLB (0.47) | POLBEPHX2GAALMNAL3MBTL1 | |
| SCHEMBL3861495 | 0.86 | POLB (0.69) | POLBEPHX2GAALMNABTK | |
| SCHEMBL12832274 | 0.85 | EPHX2 (0.56) | EPHX2GAALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL30282890 | 0.84 | POLB (0.50) | POLBEPHX2GAALMNAL3MBTL1 | |
| SCHEMBL103961 | 0.83 | — | — | |
| SCHEMBL13275171 | 0.82 | SMYD3 (0.48) | POLBEPHX2GAALMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL21640247 | 0.82 | POLB (0.48) | POLBEPHX2GAALMNAL3MBTL1 | |
| SCHEMBL15404684 | 0.82 | POLB (0.40) | POLBEPHX2GAALMNAHSD17B10 | |
| SCHEMBL12526000 | 0.82 | SMYD3 (0.48) | POLBEPHX2GAALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113698395-B | Transforming growth factor receptor antagonist, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-12-08 | — | — | CN | disclosed |