Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 6/20 | 0.48 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29131058 | 0.90 | POLB (0.57) | POLBBTKEPHX2GAALMNA | |
| SCHEMBL21490070 | 0.86 | POLB (0.57) | POLBSMYD3EPHX2LMNAALDH1A1 | |
| SCHEMBL19701343 | 0.86 | POLB (0.57) | POLBSMYD3EPHX2LMNAALDH1A1 | |
| SCHEMBL3210529 | 0.86 | POLB (0.57) | POLBSMYD3EPHX2LMNAALDH1A1 | |
| SCHEMBL3399349 | 0.86 | POLB (0.57) | POLBSMYD3EPHX2LMNAALDH1A1 | |
| SCHEMBL8235358 | 0.86 | POLB (0.57) | POLBSMYD3EPHX2LMNAALDH1A1 | |
| SCHEMBL3210521 | 0.86 | POLB (0.57) | POLBSMYD3EPHX2LMNAALDH1A1 | |
| SCHEMBL12526000 | 0.85 | SMYD3 (0.48) | POLBSMYD3BTKEPHX2GAA | |
| SCHEMBL13275171 | 0.85 | SMYD3 (0.48) | POLBSMYD3BTKEPHX2GAA | |
| Hydrochloric Acid SCHEMBL987519 | 0.84 | POLB (0.55) | POLBSMYD3LMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008028860-A1 | BENZOTRIAZOLE KINASE MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-13 | — | — | WO | disclosed |