Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | NAMPT | P43490 | 8/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11614852 | 0.98 | SMN1; SMN2 (0.81) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| Sulfur Dioxide SCHEMBL28161711 | 0.94 | SMN1; SMN2 (0.75) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL12335465 | 0.89 | NAMPT (0.75) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL165070 | 0.88 | NAMPT (1.00) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL12335476 | 0.88 | NAMPT (0.73) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL12334630 | 0.88 | NAMPT (0.81) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL18317385 | 0.87 | POLB (0.80) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL28111895 | 0.87 | NAMPT (1.00) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL12334898 | 0.87 | NAMPT (0.80) | NAMPTMEN1KMT2ACYP2C9POLB | |
| SCHEMBL29684017 | 0.86 | NAMPT (0.76) | SMN1; SMN2L3MBTL1NAMPTCYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114144230-B | Macrocyclic azolopyridine derivatives as EED and PRC2 modulators | 弗尔康医疗公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-117695280-A | Pyridin-2 (1H) -one quinolinone derivatives as mutant isocitrate dehydrogenase inhibitors | 福马治疗股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-111909130-B | Pyridin-2 (1H) -one quinolinone derivatives as mutant isocitrate dehydrogenase inhibitors | 福马治疗股份有限公司 | 2023-10-31 | — | — | CN | disclosed |