SCHEMBL29131345

SCHEMBL29131345

O=[PH](OC[S@@+]([O-])Cc1ccccc1F)OC[S@@+]([O-])Cc1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.39
IDO1 P14902 2/20 0.37
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
MMP1 P03956 1/20 0.32
MMP2 P08253 1/20 0.32
MMP9 P14780 1/20 0.32
MMP12 P39900 1/20 0.32
MAOB P27338 4/20 0.32
RIPK1 Q13546 1/20 0.31
PARP15 Q460N3 1/20 0.31
PARP14 Q460N5 1/20 0.31
PARP10 Q53GL7 1/20 0.31
KMT2A Q03164 1/20 0.30
CXCL8 P10145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29131347 0.88 TAAR1 (0.37) TAAR1IDO1LMNAALDH1A1L3MBTL1
SCHEMBL29131275 0.81 TAAR1 (0.38) TAAR1IDO1
SCHEMBL778620 0.78 TAAR1 (0.48) TAAR1IDO1LMNAALDH1A1L3MBTL1
SCHEMBL30837412 0.78 TAAR1 (0.48) TAAR1IDO1LMNAALDH1A1L3MBTL1
SCHEMBL29131384 0.76 CES2 (0.33) TAAR1IDO1MAOB
SCHEMBL11629714 0.76 CES2 (0.33) TAAR1IDO1MAOB
SCHEMBL777757 0.69 TAAR1 (0.39) TAAR1IDO1LMNAALDH1A1L3MBTL1
SCHEMBL29131278 0.69 TAAR1 (0.36) TAAR1IDO1
SCHEMBL26622181 0.67 TAAR1 (0.45) TAAR1IDO1LMNAALDH1A1L3MBTL1
SCHEMBL775353 0.67 TAAR1 (0.45) TAAR1IDO1LMNAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117303992-A Preparation method of polyfunctional group substituted chiral sulfoxide compound 厦门大学 2023-12-29 CN disclosed