Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27082311 | 0.86 | JAK2 (0.30) | JAK2JAK1 | |
| SCHEMBL27082296 | 0.84 | — | — | |
| SCHEMBL16841007 | 0.73 | — | — | |
| SCHEMBL24679 | 0.72 | — | — | |
| SCHEMBL5661212 | 0.71 | DPP4 (0.33) | JAK2JAK1 | |
| SCHEMBL23547603 | 0.69 | ATM (0.44) | JAK2JAK1 | |
| SCHEMBL819979 | 0.69 | — | — | |
| SCHEMBL20678883 | 0.68 | — | — | |
| SCHEMBL1766402 | 0.68 | — | — | |
| SCHEMBL7844383 | 0.68 | MDM2 (0.38) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098759-A | Heterocyclic compounds and their use | 组合化学工业株式会社 | 2023-11-21 | — | — | CN | disclosed |