⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820325 | 0.86 | — | — | |
| SCHEMBL820894 | 0.86 | — | — | |
| SCHEMBL15139927 | 0.86 | — | — | |
| SCHEMBL15137361 | 0.86 | — | — | |
| SCHEMBL15139926 | 0.86 | — | — | |
| SCHEMBL6618 | 0.84 | — | — | |
| SCHEMBL28823871 | 0.84 | — | — | |
| SCHEMBL1164553 | 0.84 | KDM4E (0.34) | — | |
| SCHEMBL29771365 | 0.84 | — | — | |
| SCHEMBL45941 | 0.84 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382241-B1 | POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS | BRIDGESTONE CORP (JP) | 2016-11-23 | — | — | EP | claimed |
| US-8785566-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2014-07-22 | — | — | US | claimed |
| EP-0638080-A4 | 7-DISUBSTITUTED-METHYL-4-OXO-3H -,5H --PYRROLO 3,2-d -]PYRIMIDINE AND PHARMACEUTICAL USES AND COMPOSITIONS CONTAINING THE SAME. | BIOCRYST PHARM INC (US) | 1995-08-23 | — | — | EP | claimed |
| EP-0500653-A4 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST INC (US) | 1995-08-23 | — | — | EP | claimed |
| EP-0638080-A1 | 7-DISUBSTITUTED-METHYL-4-OXO-3H -,5H --PYRROLO 3,2-d -]PYRIMIDINE AND PHARMACEUTICAL USES AND COMPOSITIONS CONTAINING THE SAME | BIOCRYST PHARMACEUTICALS, INC. (US) | 1995-02-15 | — | — | EP | claimed |
| WO-1993021187-A1 | 7-DISUBSTITUTED-METHYL-4-OXO-3H^_,5H^_-PYRROLO[3,2-d^_]PYRIMIDINE AND PHARMACEUTICAL USES AND COMPOSITIONS CONTAINING THE SAME | BIOCRYST PHARMACEUTICALS, INC. (US) | 1993-10-28 | — | — | WO | claimed |
| EP-0500653-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | claimed |
| WO-1991006548-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST, INC. (US) | 1991-05-16 | — | — | WO | claimed |
| US-4215068-A | Preparation of 1,3-dicyanocyclopentane | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-07-29 | — | — | US | claimed |
| EP-3184171-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10144752-B2 | Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use to oligomerize or polymerize olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2018-12-04 | — | — | US | disclosed |
| US-10081688-B2 | Polymers functionalized with polycyano compounds | BRIDGESTONE CORPORATION (JP) | 2018-09-25 | — | — | US | disclosed |
| EP-3373375-A1 | USE OF ALIPHATIC DINITRILES IN ELECTROCHEMICAL CELLS FOR REDUCING METAL LEACHING | BASF SE (DE) | 2018-09-12 | — | — | EP | disclosed |
| US-20170305945-A1 | Phosphinyl Amidine Compounds, Metal Complexes, Catalyst Systems, and Their Use to Oligomerize or Polymerize Olefins | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2017-10-26 | — | — | US | disclosed |
| US-5189039-A | 7-disubstituted-methyl-4-oxo-3H,5H-pyrrolo[3,2d]pyrimidine and pharmaceutical uses and compositions containing the same | BIOCRYST, INC. (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0500653-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991006548-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST, INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| US-4215068-A | Preparation of 1,3-dicyanocyclopentane | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4215068-A | Preparation of 1,3-dicyanocyclopentane | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| US-4215068-A | Preparation of 1,3-dicyanocyclopentane | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1980-07-29 | — | — | US | disclosed |