Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673730 | 0.88 | — | — | |
| SCHEMBL6672019 | 0.80 | TSHR (0.48) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL29384354 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL3676407 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL8785965 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL6673537 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL29381466 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL31135174 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL29381599 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR | |
| SCHEMBL29383760 | 0.78 | TSHR (0.52) | MAPTABCC4ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117320762-A | Packaging solution | 博士伦爱尔兰有限公司 | 2023-12-29 | — | — | CN | disclosed |