Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 1.00 |
| ▸ | CA2 | P00918 | 1/20 | 1.00 |
| ▸ | CA9 | Q16790 | 1/20 | 1.00 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | LDHA | P00338 | 2/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.40 |
| ▸ | LDHB | P07195 | 1/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL570968 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL11066368 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL1250901 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL6478072 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL9672524 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL7794 | 1.00 | — | — | |
| Bicarbonate SCHEMBL8322803 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL570721 | 1.00 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL15271537 | 1.00 | — | — | |
| Bicarbonate SCHEMBL1179 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117186540-A | Phosphorus-containing hydrophilic master batch, preparation method and application | 中化石化销售有限公司 | 2023-12-08 | — | — | CN | disclosed |