Tetrahydrofuran

Tetrahydrofuran

SCHEMBL29131759

Brc1ccc2cc(Br)ccc2c1.C1CCOC1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.52
MAPT P10636 3/20 0.48
ALDH1A1 P00352 2/20 0.48
KMT2A Q03164 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.47
BLM P54132 1/20 0.47
MAPK1 P28482 1/20 0.42
AHR P35869 3/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
BACE1 P56817 2/20 0.38
RXFP1 Q9HBX9 1/20 0.36
CYP11B1 P15538 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28027746 0.92 CYP2A6 (0.68) CYP2A6MAPTALDH1A1KMT2AKDM4E
Tetrahydrofuran SCHEMBL18167757 0.90 CYP2A6 (0.65) CYP2A6MAPTALDH1A1KMT2AKDM4E
SCHEMBL29353067 0.79 CYP2A6 (0.77) CYP2A6MAPTALDH1A1KMT2AKDM4E
SCHEMBL192166 0.79 CYP2A6 (0.77) CYP2A6MAPTALDH1A1KMT2AKDM4E
Tetrahydrofuran SCHEMBL28193777 0.78 HTT (0.43) MAPTALDH1A1LMNAHTTBLM
Tetrahydrofuran SCHEMBL29156511 0.76 METAP1 (0.47) MAPTLMNAHTTBLMMAPK1
SCHEMBL17631851 0.74 MAPT (0.59) MAPTALDH1A1KMT2AKDM4EMEN1
SCHEMBL23312077 0.73 CYP2A6 (0.68) CYP2A6MAPTALDH1A1KMT2AKDM4E
SCHEMBL17849089 0.73 CYP2A6 (0.68) CYP2A6MAPTALDH1A1KMT2AKDM4E
SCHEMBL13153611 0.73 CYP2A6 (0.68) CYP2A6MAPTALDH1A1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116813668-A Compound, light-emitting device including the same, and display device 广东聚华印刷显示技术有限公司 2023-09-29 CN disclosed