Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28027746

Brc1ccc2ccccc2c1.C1CCOC1

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.68
MAPT P10636 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 2/20 0.41
LMNA P02545 1/20 0.41
BLM P54132 1/20 0.41
MAPK1 P28482 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
PKM P14618 1/20 0.36
TSHR P16473 1/20 0.36
KDM1A O60341 1/20 0.36
RCOR1 Q9UKL0 1/20 0.36
AHR P35869 1/20 0.36
AKR1C3 P42330 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL18167757 0.98 CYP2A6 (0.65) CYP2A6MAPTMEN1KMT2AKDM4E
Tetrahydrofuran SCHEMBL29131759 0.92 CYP2A6 (0.52) CYP2A6MAPTMEN1KMT2AKDM4E
SCHEMBL29485684 0.82 CYP2A6 (1.00) CYP2A6MAPTMEN1KMT2AKDM4E
SCHEMBL154221 0.82 CYP2A6 (1.00) CYP2A6MAPTMEN1KMT2AKDM4E
SCHEMBL29002798 0.80 CYP2A6 (0.94) CYP2A6MAPTMEN1KMT2AKDM4E
SCHEMBL1120140 0.80 CYP2A6 (0.94) CYP2A6MAPTMEN1KMT2AKDM4E
SCHEMBL22909955 0.80 CYP2A6 (0.94) CYP2A6MAPTMEN1KMT2AKDM4E
Benzene SCHEMBL27861653 0.80 CYP2A6 (0.94) CYP2A6MAPTMEN1KMT2AKDM4E
Anthracene SCHEMBL1255911 0.80 ALDH1A1 (0.44) CYP2A6MAPTMEN1KMT2AALDH1A1
Naphthalene SCHEMBL10617947 0.80 ALDH1A1 (0.50) CYP2A6MEN1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843427-A Synthesis method of axisymmetric dinaphthylcyclopentene fused tetraphenyl 内蒙古大学 2024-04-09 CN disclosed
CN-104844654-B A kind of quaternary salt compounds and preparation method thereof 昆明理工大学 2016-11-02 CN disclosed
CN-104844654-A Quaternary phosphonium salt compound and preparation method thereof UNIV KUNMING SCIENCE & TECHNOLOGY 2015-08-19 CN disclosed