Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772816 | 0.80 | PTGDR2 (0.35) | MAPTALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29131784 | 0.78 | ALDH1A1 (0.39) | KMT2AMEN1MAPTALDH1A1BRD4 | |
| SCHEMBL19626252 | 0.75 | PDE4A (0.37) | KMT2AMAPTBRD4PDE4APDE4B | |
| SCHEMBL29131772 | 0.73 | TP53 (0.39) | KMT2AMEN1MAPTALDH1A1PTPN11 | |
| SCHEMBL16608400 | 0.72 | PDE4A (0.37) | PTPN11BRD4PDE4APDE4BPDE4C | |
| SCHEMBL29131776 | 0.69 | NPC1 (0.40) | KMT2AMEN1MAPTALDH1A1BRD4 | |
| SCHEMBL30877446 | 0.69 | ALDH1A1 (0.40) | KMT2AMEN1MAPTALDH1A1BRD4 | |
| SCHEMBL30877347 | 0.67 | CYP3A4 (0.38) | KMT2AMEN1MAPTALDH1A1BRD4 | |
| SCHEMBL30877423 | 0.66 | ALDH1A1 (0.39) | KMT2AMEN1MAPTALDH1A1BRD4 | |
| SCHEMBL30877462 | 0.65 | ALDH1A1 (0.42) | MAPTALDH1A1GAABRD4NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098763-A | TYK2 inhibitors | 渤健马萨诸塞州股份有限公司 | 2023-11-21 | — | — | CN | disclosed |