Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29132076 | 1.00 | NR1H2 (0.45) | NR1H2NAMPTGPR119USP2SMN1; SMN2 | |
| SCHEMBL26926054 | 0.90 | KDM4E (0.45) | NR1H2GPR119USP2SMN1; SMN2KDM4E | |
| SCHEMBL26926233 | 0.90 | KDM4E (0.45) | NR1H2GPR119USP2SMN1; SMN2KDM4E | |
| SCHEMBL26926046 | 0.90 | KDM4E (0.45) | NR1H2GPR119USP2SMN1; SMN2KDM4E | |
| SCHEMBL28721922 | 0.85 | NR1H2 (0.48) | NR1H2GPR119USP2SMN1; SMN2MEN1 | |
| SCHEMBL28721924 | 0.85 | NR1H2 (0.48) | NR1H2GPR119USP2SMN1; SMN2MEN1 | |
| SCHEMBL28938073 | 0.85 | NR1H2 (0.48) | NR1H2GPR119USP2SMN1; SMN2MEN1 | |
| SCHEMBL29132091 | 0.81 | KDM4E (0.44) | GPR119KDM4EPKMALDH1A1MAPT | |
| SCHEMBL25338213 | 0.81 | NR1H2 (0.49) | NR1H2NAMPTGPR119USP2SMN1; SMN2 | |
| SCHEMBL23860095 | 0.81 | USP2 (0.42) | NR1H2USP2SMN1; SMN2ALDH1A1SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |