Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26926046 | 0.89 | KDM4E (0.45) | KDM4EPKMGPR119HPGDALDH1A1 | |
| SCHEMBL26926054 | 0.89 | KDM4E (0.45) | KDM4EPKMGPR119HPGDALDH1A1 | |
| SCHEMBL26926233 | 0.89 | KDM4E (0.45) | KDM4EPKMGPR119HPGDALDH1A1 | |
| SCHEMBL23860095 | 0.85 | USP2 (0.42) | HPGDALDH1A1RECQL | |
| SCHEMBL29927363 | 0.82 | PDK1 (0.50) | KDM4EPKMGPR119FAAHNPC1 | |
| SCHEMBL29132073 | 0.81 | NR1H2 (0.45) | KDM4EPKMGPR119HPGDALDH1A1 | |
| SCHEMBL29132076 | 0.81 | NR1H2 (0.45) | KDM4EPKMGPR119HPGDALDH1A1 | |
| SCHEMBL29132150 | 0.80 | SETD7 (0.36) | GPR119HPGD | |
| SCHEMBL29132190 | 0.78 | ITGB3 (0.40) | — | |
| SCHEMBL15217058 | 0.78 | SETD7 (0.42) | GPR119HPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |