Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 11/20 | 0.51 |
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29927550 | 1.00 | CRBN (0.59) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL31653793 | 0.96 | CRBN (0.60) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL26125102 | 0.96 | CRBN (0.60) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL23249883 | 0.96 | CRBN (0.62) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL29132103 | 0.93 | CRBN (0.59) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL29927587 | 0.93 | CRBN (0.59) | CRBNDDB1HPGDSARALDH1A1 | |
| SCHEMBL29132051 | 0.90 | CRBN (0.54) | CRBNDDB1HPGDSARRAF1 | |
| SCHEMBL29928061 | 0.90 | CRBN (0.54) | CRBNDDB1HPGDSARRAF1 | |
| SCHEMBL29132293 | 0.89 | CRBN (0.56) | CRBNDDB1HPGDSARRAF1 | |
| SCHEMBL29927878 | 0.89 | CRBN (0.56) | CRBNDDB1HPGDSARRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |