Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.42 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23836645 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775013 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775015 | 0.98 | GRIK1 (0.51) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775024 | 0.93 | SLC1A2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775019 | 0.93 | SLC1A2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775012 | 0.93 | SLC1A2 (0.50) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL25006715 | 0.86 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18762598 | 0.85 | SLC1A2 (0.44) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775003 | 0.85 | SLC1A2 (0.44) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 | |
| SCHEMBL18775000 | 0.85 | SLC1A2 (0.44) | GRIK1GRIK2SLC1A2SLC1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300115-A1 | USE OF INDUCTOR AGENTS GSE24.2 FOR PRODUCING PHARMACEUTICAL COMPOSITIONS FOR TREATING ILLNESSES RELATING TO CELLULAR SENESCENCE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) | 2011-12-08 | — | — | US | disclosed |
| EP-2216043-A1 | USE OF INDUCTOR AGENTS GSE24.2 FOR PRODUCING PHARMACEUTICAL COMPOSITIONS FOR TREATING ILLNESSES RELATING TO CELLULAR SENESCENCE | Consejo Superior De Investigaciones Científicas (ES) | 2010-08-11 | — | — | EP | disclosed |