SCHEMBL23836645

SCHEMBL23836645

CCCCCCC(C)(C)C[C@H](N)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.53
GRIK2 Q13002 2/20 0.53
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
SLC1A3 P43003 1/20 0.47
FFAR1 O14842 2/20 0.42
CPT2 P23786 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NOD1 Q9Y239 2/20 0.42
DDAH1 O94760 1/20 0.41
GPR84 Q9NQS5 3/20 0.40
KIF11 P52732 1/20 0.39
MAPT P10636 1/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18775013 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL2913235 1.00 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18775015 0.98 GRIK1 (0.51) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18775024 0.93 SLC1A2 (0.50) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18775019 0.93 SLC1A2 (0.50) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18775012 0.93 SLC1A2 (0.50) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL25006715 0.86 GRIK1 (0.53) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18762598 0.85 SLC1A2 (0.44) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18775003 0.85 SLC1A2 (0.44) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL18775000 0.85 SLC1A2 (0.44) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210337850-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS LUCTA, S.A. (ES) 2021-11-04 US disclosed
US-11124525-B2 Heteroaryl compounds useful as MK2 inhibitors CELGENE CAR LLC (BM) 2021-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210337850-A1 SAVOURY AND MOUTHFULNESS TASTE ENHANCERS KCNJ6, TAS1R1, TAS2R5 GRIK1 98/4885GRIK2 215/4885SLC1A2 4049/4885
US-11124525-B2 Heteroaryl compounds useful as MK2 inhibitors MKNK2, MKRN3, MKNK1 GRIK1 847/4885GRIK2 170/4885SLC1A2 3669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.