Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212462 | 0.93 | GPR119 (0.55) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL216692 | 0.91 | GPR119 (0.58) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL17221458 | 0.87 | GPR119 (0.54) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL13832628 | 0.85 | GPR119 (0.51) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL13832841 | 0.85 | GPR119 (0.51) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL1502200 | 0.85 | GPR119 (0.51) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL25213322 | 0.83 | GPR119 (0.58) | GPR119MMP13KMT2A | |
| SCHEMBL184777 | 0.82 | CYP2D6 (0.60) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL344871 | 0.82 | KMT2A (0.49) | GPR119MMP13KMT2AMEN1 | |
| SCHEMBL21997972 | 0.82 | GPR119 (0.56) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4308557-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117321046-A | Indazole-based compounds and related methods of use | 阿维纳斯企业公司 | 2023-12-29 | — | — | CN | disclosed |
| WO-2022198112-A1 | INDAZOLE BASED COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-09-22 | — | — | WO | disclosed |