Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26116351 | 0.86 | MAPT (0.40) | ALDH1A1MAPTNPSR1SMN1; SMN2PKM | |
| SCHEMBL2078818 | 0.84 | TP53 (0.49) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL8076838 | 0.84 | TP53 (0.49) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL20293456 | 0.84 | TP53 (0.49) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL16685914 | 0.76 | TP53 (0.42) | TP53ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL371909 | 0.72 | MEN1 (0.36) | ALDH1A1GAACCR2 | |
| SCHEMBL29132538 | 0.72 | TP53 (0.32) | TP53ALDH1A1 | |
| SCHEMBL12526267 | 0.71 | SMN1; SMN2 (0.41) | TP53ALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL15515961 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDGAASMN1; SMN2 | |
| SCHEMBL15515818 | 0.70 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829570-A | WEE1 degrading compounds | 北京星奇原生物科技有限公司 | 2023-09-29 | — | — | CN | disclosed |