Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725240 | 0.81 | TDP1 (0.48) | GPR35CA1CA2MMP1MMP2 | |
| SCHEMBL4725431 | 0.81 | TDP1 (0.46) | GPR35TDP1NPC1RAB9ACXCR2 | |
| SCHEMBL4725420 | 0.81 | TDP1 (0.46) | GPR35TDP1NPC1RAB9ACXCR2 | |
| SCHEMBL601548 | 0.80 | KMT2A (0.50) | GPR35TDP1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL30625900 | 0.80 | KMT2A (0.50) | GPR35TDP1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL309307 | 0.78 | RAB9A (0.51) | GPR35TDP1NPC1RAB9AMAPT | |
| SCHEMBL3450046 | 0.77 | TDP1 (0.44) | GPR35TDP1NPC1RAB9AMAPT | |
| SCHEMBL4055608 | 0.77 | MEN1 (0.49) | TDP1NPC1RAB9ACXCR2MAPT | |
| SCHEMBL4947111 | 0.77 | CXCR2 (0.58) | TDP1CXCR2MAPTMAPK1L3MBTL1 | |
| SCHEMBL2507487 | 0.76 | MAPT (0.44) | GPR35TDP1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117203202-A | Quinoxaline derivative and use thereof | 黑钻治疗公司 | 2023-12-08 | — | — | CN | disclosed |