Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 7/20 | 0.54 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033214 | 1.00 | AXL (0.54) | AXLCAMKK2FFAR4MAP2K1AAK1 | |
| SCHEMBL23925207 | 0.90 | AXL (0.46) | AXLCAMKK2FFAR4MAP2K1AAK1 | |
| SCHEMBL30287304 | 0.88 | AXL (0.45) | AXLCAMKK2FFAR4MAP2K1AAK1 | |
| SCHEMBL23925237 | 0.88 | AXL (0.45) | AXLCAMKK2FFAR4MAP2K1AAK1 | |
| SCHEMBL29100095 | 0.85 | AXL (0.46) | AXLCAMKK2AAK1SGK1 | |
| SCHEMBL29132818 | 0.84 | AXL (0.39) | AXLCAMKK2AAK1 | |
| SCHEMBL523456 | 0.80 | CDK8 (0.49) | FFAR4 | |
| SCHEMBL31427495 | 0.80 | CDK8 (0.49) | FFAR4 | |
| SCHEMBL1958630 | 0.78 | FFAR4 (0.46) | AXLFFAR4 | |
| SCHEMBL1956720 | 0.77 | FFAR4 (0.47) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981668-A | Process for preparing intermediates for BCL-2 inhibitors | 百济神州(北京)生物科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116981668-A | Process for preparing intermediates for BCL-2 inhibitors | 百济神州(北京)生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |