Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | PYGM | P11217 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29100095 | 0.85 | AXL (0.46) | AXLCAMKK2PYGLPYGMAAK1 | |
| SCHEMBL29132816 | 0.84 | AXL (0.54) | AXLCAMKK2AAK1 | |
| SCHEMBL30033214 | 0.84 | AXL (0.54) | AXLCAMKK2AAK1 | |
| SCHEMBL23925237 | 0.75 | AXL (0.45) | AXLCAMKK2AAK1 | |
| SCHEMBL30287304 | 0.75 | AXL (0.45) | AXLCAMKK2AAK1 | |
| SCHEMBL19692583 | 0.75 | CDK8 (0.47) | AXL | |
| SCHEMBL23925207 | 0.74 | AXL (0.46) | AXLCAMKK2AAK1 | |
| SCHEMBL31368049 | 0.70 | JAK2 (0.46) | AXLPAK1PKMCYP2C9CYP2C19 | |
| SCHEMBL2814713 | 0.69 | AXL (0.47) | AXLCAMKK2KDM4E | |
| SCHEMBL23541592 | 0.69 | AXL (0.52) | AXLCAMKK2PAK1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981668-A | Process for preparing intermediates for BCL-2 inhibitors | 百济神州(北京)生物科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-116981668-A | Process for preparing intermediates for BCL-2 inhibitors | 百济神州(北京)生物科技有限公司 | 2023-10-31 | — | — | CN | disclosed |