Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30703605 | 1.00 | NISCH (0.37) | NISCHKDM4ERAB9ANPC1MAPT | |
| SCHEMBL29609730 | 0.77 | MAPT (0.44) | KDM4ERAB9ANPC1MAPTKMT2A | |
| SCHEMBL3584585 | 0.77 | MAPT (0.44) | KDM4ERAB9ANPC1MAPTKMT2A | |
| SCHEMBL2123963 | 0.73 | CYP2A6 (0.48) | RAB9ANPC1MAPTKMT2ACYP1A2 | |
| SCHEMBL3584065 | 0.73 | HSP90AA1 (0.39) | NISCHKDM4ECYP1A2CYP2C9ALDH1A1 | |
| SCHEMBL26350335 | 0.73 | PDE10A (0.40) | KDM4ERAB9ANPC1MAPTKMT2A | |
| SCHEMBL3576610 | 0.72 | MEN1 (0.43) | KDM4ERAB9ANPC1MAPTXDH | |
| SCHEMBL5264555 | 0.71 | ALDH1A1 (0.32) | KDM4ERAB9ANPC1MAPTKMT2A | |
| SCHEMBL27720027 | 0.71 | MAPT (0.41) | KDM4ERAB9ANPC1MAPTAGTR1 | |
| SCHEMBL27836857 | 0.71 | ALDH1A1 (0.39) | NPC1MAPTAGTR1XDHTXNRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099899-B | Oxazole derivatives useful as IRAK inhibitors and process for their preparation | 里格尔药品股份有限公司 | 2024-01-02 | — | — | CN | disclosed |