Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 19/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.42 |
| ▸ | PAICS | P22234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20090309 | 1.00 | IRAK4 (0.43) | IRAK4IRAK1PAICS | |
| SCHEMBL30703612 | 1.00 | IRAK4 (0.43) | IRAK4IRAK1PAICS | |
| SCHEMBL20090337 | 0.93 | IRAK4 (0.44) | IRAK4IRAK1 | |
| SCHEMBL20090319 | 0.93 | IRAK4 (0.40) | IRAK4IRAK1 | |
| SCHEMBL30259930 | 0.93 | IRAK4 (0.40) | IRAK4IRAK1 | |
| SCHEMBL24780933 | 0.93 | IRAK4 (0.40) | IRAK4IRAK1 | |
| SCHEMBL20161246 | 0.93 | IRAK4 (0.44) | IRAK4IRAK1 | |
| SCHEMBL20090302 | 0.90 | IRAK4 (0.46) | IRAK4IRAK1 | |
| SCHEMBL20161141 | 0.90 | IRAK4 (0.46) | IRAK4IRAK1 | |
| SCHEMBL21407126 | 0.90 | IRAK4 (0.53) | IRAK4IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110099899-B | Oxazole derivatives useful as IRAK inhibitors and process for their preparation | 里格尔药品股份有限公司 | 2024-01-02 | — | — | CN | disclosed |