Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622218 | 1.00 | KDM4E (0.48) | KDM4ENPC1RAB9APKMMAPT | |
| SCHEMBL17194922 | 0.82 | TLR8 (0.40) | KDM4ENPC1RAB9APKMMAPT | |
| SCHEMBL18415070 | 0.78 | TYK2 (0.37) | NPC1RAB9AMAPTTYK2HTR2C | |
| SCHEMBL20150102 | 0.78 | TYK2 (0.37) | NPC1RAB9AMAPTTYK2HTR2C | |
| SCHEMBL20230885 | 0.78 | TYK2 (0.46) | KDM4ENPC1RAB9AMAPTTYK2 | |
| SCHEMBL24026469 | 0.78 | TYK2 (0.39) | TYK2P2RX7HTR2CHTR2AMEN1 | |
| SCHEMBL20472405 | 0.78 | CNR2 (0.47) | P2RX7 | |
| SCHEMBL30622217 | 0.77 | SMN1; SMN2 (0.36) | KDM4EP2RX7HTR2CHTR2AKMT2A | |
| SCHEMBL29133091 | 0.77 | SMN1; SMN2 (0.36) | KDM4EP2RX7HTR2CHTR2AKMT2A | |
| SCHEMBL10765944 | 0.77 | IDO1 (0.46) | KDM4ENPC1RAB9AHTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |