Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.33 |
| ▸ | FEN1 | P39748 | 3/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622210 | 1.00 | ALOX5AP (0.33) | ALOX5APFEN1CASP6NOTUMSOS1 | |
| SCHEMBL30622217 | 0.82 | SMN1; SMN2 (0.36) | CYP2D6CYP2C19ADRA1A | |
| SCHEMBL29133091 | 0.82 | SMN1; SMN2 (0.36) | CYP2D6CYP2C19ADRA1A | |
| SCHEMBL29132962 | 0.70 | NOTUM (0.33) | NOTUM | |
| SCHEMBL30622266 | 0.70 | NOTUM (0.33) | NOTUM | |
| SCHEMBL29133196 | 0.69 | SLC6A2 (0.40) | NOTUM | |
| SCHEMBL30622232 | 0.69 | SLC6A2 (0.40) | NOTUM | |
| SCHEMBL25180819 | 0.68 | CASP6 (0.36) | ALOX5APFEN1CASP6SOS1 | |
| SCHEMBL29133011 | 0.67 | SCN9A (0.40) | — | |
| SCHEMBL3838896 | 0.66 | CYP2D6 (0.32) | CYP2D6CYP2C19ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |